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In parallel, Ca 2+ dysregulation, endoplasmic reticulum stress and mitochondrial dysfunction further exacerbate astrocytic impairment 114
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Here, we reformulate these emerging paradigms into our current understanding of cell death mechanisms
UA plays a crucial role in improving mitochondrial function by stimulating mitophagy and inhibiting the age-related accumulation of dysfunctional mitochondria, thereby maintaining mitochondrial biogenesis and respiration within cells (1)
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